Scientific Program

You can update your brief biography and profile picture on the [My Profile] page.

  • Session TrackBiomaterials for in vitro (extracorporeal) analysis
  • Session TitleEx vivo model systems for cancer immunotherapy
  • Session CodeSP-T07-0063
  • Date & Time / RoomMay 27 (Mon) 13:00~14:30 / Room 321-B
Organizer

Junsang Doh (Seoul National University, Korea, Republic of)

Chair

Junsang Doh (Seoul National University, Korea, Republic of)

Kyobum Kim (Dongguk Univ, Korea, Republic of)

Keynote Speaker

Susan Thomas (Georgia Tech, USA)

Invited Speaker

Junsang Doh (Seoul National University, Korea, Republic of)

Oral Presenter

13:40~13:50 : 3D in vitro models of sinonasal cancers as a personalized platform to study new drugs Serena Danti (University of Pisa, Italy)

13:50~14:00 : Cell derived extracellular matrices for tumor models for in vitro testing Elisabeth Engel (Universitat Politecnica de Catalunya, Spain)

14:00~14:10 : Hydrolytically Degradable, Micro-organoids for Spatial Patterning of Human Lymph Node Tissue Chips Valeria Juarez (Georgia Institute of Technology, USA)

14:10~14:20 : IN VITRO HYDROGEL-BASED MODELS TO OBSERVE GLIOBLASTOMA SPHEROID GROWTH, INVASION AND THERAPY RESPONSIVENESS AT MATRIX INTERFACES Eya Ferchichi (Saint Louis University, USA)

Description

Cancer immunotherapy is a novel cancer treatment approach that relies on our immune system's ability to recognize and eliminate cancer cells. Cancer immunotherapy has recently been successful in treating a variety of different types of cancer, but it is still only effective for a small percentage of cancer patients. One of the key challenges in the advancement of cancer immunotherapy is lack of preclinical models representing tumor-immune microenvironments of cancer patients. In this symposium, ex vivo engineered model systems based on organoid or organ-on-a-chip technologies recapitulating various aspects of complex and dynamic tumor-immune microenvironments will be presented.

Keywords : Cancer immunotherapy, ex vivo model system

  • Session TrackBiomaterials for in vitro (extracorporeal) analysis
  • Session TitleIn vitro microphysiological systems for studying tumor microenvironment
  • Session CodeSP-T07-0064
  • Date & Time / RoomMay 27 (Mon) 16:30~18:00 / Room 321-B
Organizer

Joo Hun Kang (UNIST, Korea, Republic of)

Chair

Joo Hun Kang (UNIST, Korea, Republic of)

Junsang Doh (Seoul National University, Korea, Republic of)

Keynote Speaker

16:30~16:55 : Microengineered Biomimicry of Human Physiological Systems Dan Dongeun Huh (University of Pennsylvania, USA)

Invited Speaker

16:55~17:10 : Engineering patient-derived microphysiological systems to reconstruct the tumor microenvironments Jihoon Ko (Gachon University, Korea, Republic of)

17:10~17:25 : Reverse Engineering of Tumor Microenvironment Using Microfluidics and 3D Printing Sungsu Park (Sungkyunkwan University, Korea, Republic of)

Oral Presenter

17:25~17:35 : Intratumoral mapping of local 3D tissue viscoelasticity at cellular clength scales during breast cancer progression Christopher Moraes (McGill University, Canada)

17:35~17:45 : Comparative analysis of 3D-printed β-TCP and freeze-dried alginate-bioactive glass scaffolds as bone-like microenvironments for osteosarcoma in vitro modelling Ksenia Menshikh (Università del Piemonte Orientale, Italy)

Description

The development of in vitro microphysiological systems have spurred the exploration of the intricate dynamics of the tumor microenvironment. This symposium aims to converge researchers on a platform designed to share insights into the latest breakthroughs in the field. 



This symposium is to provide a comprehensive overview of the current state-of-the-art in in vitro microphysiological systems utilized for investigating the tumor microenvironment. It seeks to encourage the exchange of knowledge between researchers working at the interface of biology, engineering, and medicine. Through this collaboration, participants will not only deepen their understanding of these advanced models but also explore novel approaches and technologies that enable a more accurate representation of tumor dynamics in the microenvironment. 



The symposium's program comprises a keynote presentation (Prof. Dan Dongeun Huh, Penn), an eminent researcher in the field. Diverse perspectives will be highlighted, encompassing most-advanced techniques and clinical applications. The intended audience includes researchers and practitioners across the fields of oncology, tissue engineering, biomaterials, and drug development. 



Anticipated outcomes include an enriched understanding of how in vitro microphysiological systems can replicate the intricacies of the tumor microenvironment. Insights from this symposium will drive the development of more physiologically relevant tumor in vitro models, leading to enhanced predictive capabilities for drug testing and personalized treatment. Moreover, discussions around challenges and opportunities in this field will guide future research directions, accelerating the translation of findings from bench to bedside.

Keywords : organ on a chip, tumor microenvironment, in vitro microphysiological systems

  • Session TrackBiomaterials for in vitro (extracorporeal) analysis
  • Session TitleMicrophysiological systems for modeling pathologies of central nervous system
  • Session CodeSP-T07-0065
  • Date & Time / RoomMay 28 (Tue) 9:30~11:00 / Room 321-B
Organizer

Hong Nam Kim (Korea Institute of Science and Technology, Korea, Republic of)

Chair

Hong Nam Kim (Korea Institute of Science and Technology, Korea, Republic of)

Seokyoung Bang (Dongguk University, Korea, Republic of)

Keynote Speaker

Ki Bum Lee (Rutgers University, USA)

Invited Speaker

9:55~10:10 : Refining Cultivation Techniques for Human Neural Systems with Tailored Extracellular Matrix and Microfluidic Integration Yoonhee Jin (Yonsei University College of Medicine, Korea, Republic of)

10:10~10:25 : Human spinal cord organoids exhibiting neural tube morphogenesis for a quantifiable drug screening system of neural tube defects Ju-Hyun Lee (Korea Institute of Science and Technology, Korea, Republic of)

Oral Presenter

10:25~10:35 : A 3D in vitro cortical tissue model For Studying effects of ionizing radiation on human neuronal network function Chiara E Ghezzi (University of Massachusetts Lowell, USA)

10:35~10:45 : Acoustic Stimulation in BBB-on-a-Chip: Advancing Blood-Brain Barrier Research Melanie Stamp (University of Melbourne, Australia)

Description

In this symposium, we discuss the emerging microphysiological system-based central nervous system (CNS) models and their application in CNS disease modeling. By using the engineered human CNS models, the pathophysiological features of human CNS diseases can be recapitulated and the efficacy of therapeutic approaches can be evaluated. Especially, the CNS organoid and CNS organ-on-a-chip will be presented with their merits in mimicking the CNS ultrastructure and microenvironment. This symposium may be potentially useful for those who are working on biomaterials-based tissue modeling, next-generation pharmaceutics, and innovative nano-bio technologies. This symposium is believed to widen the knowledge in biomaterials with a particular focus on microphysiological system-based human CNS disease modeling.

Keywords : Microphysiological system, central nervous system, pathology modeling

  • Session TrackBiomaterials for in vitro (extracorporeal) analysis
  • Session TitleOptical biosensors for fast and accurate diagnosis
  • Session CodeSP-T07-0070
  • Date & Time / RoomMay 29 (Wed) 9:30~11:00 / Room 321-B
Organizer

Heebeom Koo (The Catholic University of Korea, Korea, Republic of)

Chair

Heebeom Koo (The Catholic University of Korea, Korea, Republic of)

Joonhyuck Park (The Catholic University of Korea, Korea, Republic of)

Keynote Speaker

Niko Hildebrandt (Université de Rouen Normandie, France)

Invited Speaker

9:55~10:10 : Engineering cells with nanomaterials for augmenting and tracking cell-based therapies Jinhwan Kim (UC Davis, USA)

Oral Presenter

10:10~10:20 : Nanomaterial based ultrasensitive bioimaging and biosensor platforms Joonhyuck Park (The Catholic University of Korea, Korea, Republic of)

10:20~10:30 : In vitro tissue-equivalent models for studying foreign body reaction Liliana Agresti (University Medical Center Groningen (UMCG), Netherlands)

10:30~10:40 : Hydrogel-Based 3D In Vitro Model of Liver Toxicity with Simulated Human Immune System for Predicting Hepatotoxicity and Immune Hyperactivity Yu Bin Lee (Korea Institute of Toxicology, Korea, Republic of)

10:40~10:50 : Ultrasensitive Paper-based Surface-Enhanced Raman Spectroscopy for Clinical Applications DEHUI WAN (National Tsing Hua University, Chinese Taipei)

Description

Highly sensitive detection of biomolecules is of paramount importance to understanding biological functions at the single-cell level and for various medical diagnoses. Various nanoparticles (NPs) including quantum dots, upconversion NPs, gold NPs, and graphene/carbon nanotubes are useful and have been used for this purpose. Cutting-edge technologies have been developed based on the rational combination of these nano-materials, and could achieve fast and efficient sensing of many biomolecules with low concentrations.

Keywords : sensor, optical imaging, nanoparticle

  • Session TrackBiomaterials for in vitro (extracorporeal) analysis
  • Session TitleImaging and spectroscopic analysis of biomaterials and biological systems
  • Session CodeSP-T07-0075
  • Date & Time / RoomMay 28 (Tue) 13:40~15:10 / Room 321-B
Organizer

Sung Sik Lee (ETH Zurich, Switzerland)

Chair

Sung Sik Lee (ETH Zurich, Switzerland)

Jong-Chan Lee (DGIST, Korea, Republic of)

Keynote Speaker

Yong Keun Park (KAIST, Korea, Republic of)

Invited Speaker

Byung Mook Weon (Sungkyunkwan University, Korea, Republic of)

14:20~14:35 : Tackling background noise problem in STED optical nanoscopy Jong-Chan Lee (DGIST, Korea, Republic of)

14:35~14:50 : Microfluidic platform for single live sperm analysis Jae Bem You (Kyungpook National University, Korea, Republic of)

Oral Presenter

14:50~15:00 : Comprehensive Analysis of Collagen Hydrogel Response to Physiological pH Fluctuations: Structure, Viscoelasticity, and Permeability Orit Bronner Shtrauchler (Ben-Gurion University of the Negev, Israel)

15:00~15:10 : Modernizing Drug Discovery: from Organ-on-a-Chip to AI-Driven Insights Boyang Zhang (McMaster University, Canada)

Description

Imaging and spectroscopy have been used to characterize biomaterials and biological systems. The goal of this symposium is to discuss current developing imaging and spectroscopy methods and applications that could be used with in vitro (extracorporeal) analysis (e.g. lab-on-a chip, organ models, 3D culture, Healthcare devices). X-ray imaging, quantitative phase imaging, Raman spectroscopy and imaging (SERS, CARS, SRS), super-resolution imaging, label-free imaging, single molecule detection, multi-photon imaging, light-sheet imaging and advanced imaging/spectroscopy for biomaterials and biological systems (e.g. organoid, soft matter, phase separation) are among the topics covered at the symposium. In addition, the symposium could cover biocompatible imaging/spectroscopy probes, visualization and spectroscopic quantification of biomaterials in in-vitro devices as well as biological systems.    

 

Keywords : Imaging, Spectroscopy, biocompatible probe for in-vitro device

  • Session TrackBiomaterials for in vitro (extracorporeal) analysis
  • Session TitleLiquid biopsy for cancer diagnosis and prognosis
  • Session CodeSP-T07-0349
  • Date & Time / RoomMay 28 (Tue) 16:30~18:00 / Room 321-B
Organizer

Seungpyo Hong (University of Wisconsin-Madison, USA)

Chair

Seungpyo Hong (University of Wisconsin-Madison, USA)

Tian Zhang (University of Texas Southwestern Medical Center, USA)

Keynote Speaker

Andrew Wang (University of Texas Southwestern Medical Center, USA)

Invited Speaker

16:55~17:10 : Liquid Biopsy for Cancer Immunotherapy Jiyoon Bu (Inha University, Korea, Republic of)

Yong-Sang Ryu (Korea University, Korea, Republic of)

Oral Presenter

17:25~17:35 : Investigation of extrachromosomal DNA (ecDNA) activities in extracellular matrix component-based environmen SeoYul Jo (Sungkyunkwan University, Korea, Republic of)

17:35~17:45 : Living single-cell secreted multiple biomarker profiling using microfluidic chip and machine learning for tumor cell classification Yu Zhang (Shandong University, China)

17:45~17:55 : An efficient strategy for circulating tumor cell detection: surface-enhanced Raman spectroscopy Jie Lin (Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, China)

Description

Liquid biopsies are emering, given their advantages over conventional tissue biopsy and imaging, such as minimially invasiveness

Keywords : Liquid biopsy; nanotechnology; in vitro diagnsostics

  • Session TrackBiomaterials for in vitro (extracorporeal) analysis
  • Session Title3D-Tissue Models for Infection and Immunological Assays
  • Session CodeSP-T07-0122
  • Date & Time / RoomMay 29 (Wed) 13:40~15:10 / Room 321-B
Organizer

Michiya Matsusaki (Osaka University, Japan)

Chair

Michiya Matsusaki (Osaka University, Japan)

Wei Li (Texas Tech University, USA)

Keynote Speaker

Juergen Groll (University of Wuerzburg, Germany)

Invited Speaker

Kendra Rumbaugh (Texas Tech University, USA)

14:20~14:35 : Treatment of Wound Infections with Bacteria-Responsive Hydrogel-Based Drug Delivery Anita Shukla (Brown University, USA)

Oral Presenter

14:35~14:45 : Study for Changes of IL-1α and IL-8 of RhE Model in vitro skin irritation test for medical devices Liu Jia (Shan Dong Institute of Medical Device and Pharmaceutical Packaging Inspection, China)

14:45~14:55 : Brain organoid-on-a-chip platform to spatiotemporally model virus infection via neuronal crosstalk Ann-Na Cho (University of Sydney, Australia)

14:55~15:05 : Micro-structured mechano-mimetic biomaterials for engineering the thymic niche Ludovica Cacopardo (University of Pisa, Italy)

Description

1) Objective of this symposium is to discuss the possibility and future direction of static and dinamic 3D-tissue models for the assessment of in vivo infection and immunological reactions.

2) This symposium invites one keynote and three invited speakers who are the world leading researcher in the fields of biofabrication, tissue engineering, biomaterials, microfluidic systems, and nanomaterials for infection and immunology.

3) Expected outcomes and relevance to the main topic of WBC 2024 is the participating experts can gather and share the latest information and knowledge in the recent hot and important areas of biomaterials research for infection and immunology.

Keywords : 3D-tissue models, infection assay, immunological assay

  • Session TrackBiomaterials for in vitro (extracorporeal) analysis
  • Session TitleBiomaterial-based platforms for tumor tissue engineering
  • Session CodeSP-T07-0174
  • Date & Time / RoomMay 29 (Wed) 16:30~18:00 / Room 321-B
Organizer

Daniela Loessner (Monash University, Australia)

Chair

Daniela Loessner (Monash University, Australia)

Carsten Werner (Leibniz Institute for Polymer Research, Germany)

Keynote Speaker

16:30~16:55 : Modelling complex interactions in the tumour microenvironment Claus Jorgensen (The University of Manchester, United Kingdom)

Invited Speaker

16:55~17:10 : Mineralized cryogels to recapitulate early events of breast cancer bone metastasis in vitro Carsten Werner (Leibniz Institute for Polymer Research, Germany)

Oral Presenter

17:10~17:20 : Construction of vascularized gastric cancer organoid-on-chip model via combining elastin-based hydrogels and 3D printing Leping Yan (The Seventh Affiliated Hospital, Sun Yat-sen University, China)

17:20~17:30 : Tumor-mimetic gradients in collagen fiber alignment enhance endothelial and cancer cell migration directionality and persistance Vinay Abhyankar (Rochester Institute of Technology, USA)

17:30~17:40 : AI Augmented 4D Bio-printed High-performance Invitro Disease Model of Oral Submucous Fibrosis. KANIKA SINGROHA (All India Institute of Medical Sciences Jodhpur- Indian Institute of TechnologyJodhpur, India)

17:40~17:50 : Spatially controlled construction of assembloids for modeling glioma infiltration Michelle Huang (Stanford University, USA)

Description

Tissue engineering technologies have produced innovative tools for cancer research. 3D cancer models based on molecularly designed biomaterials aim to harness the dimensionality, biomechanical and biochemical properties of tumor tissues. However, to date, in spite of the critical role that the extracellular matrix plays in cancer, only the minority of 3D cancer models is built on biomaterial-based matrices. Major reasons for avoiding this critical design feature are the difficulty to recreate the inherent complexity of the tumor microenvironment and the limited availability of practical analytical and validation techniques. Recent advances emerging at the interface of supramolecular chemistry, materials science and tumor biology are generating new approaches to overcome these boundaries and enable the design of physiologically relevant 3D models. In this symposium, we discuss how these 3D systems are applied to deconstruct and engineer the tumor microenvironment, opening opportunities to model primary tumors, metastasis and responses to anti-cancer treatment.



Objectives: The main goal of our symposium is to inform the audience about the emerging discipline of tumor tissue engineering. Therefore, we have several objectives: i) introduce the concept of tumor tissue engineering, ii) describe key parameters in tumor biology and iii) tools for rebuilding the tumor microenvironment, and iv) present novel applications of tumor-engineered models to investigate primary tumors, metastasis and anti-cancer treatment.



Audience: Our symposium targets an interdisciplinary audience that includes materials and polymer scientists, engineers, as well as biologists and life scientists.



Relevance to the main topic of WBC 2024: Our symposium is strategically aligned with the topic of WBC 2024. Biology can help to design materials and approaches for tumor tissue engineering. Biomaterials are a requisite for modeling cancer to rebuild tissue organisation, composition and function. In our symposium, we present bioengineering strategies that recreate the pathophysiology of cancer to address questions in cancer research and healthcare.

Keywords : tissue engineering, biomaterials, tumor biology, 3D cancer models, tumor microenvironment, extracellular matrix

  • Session TrackBiomaterials for in vitro (extracorporeal) analysis
  • Session TitleBiomaterials for Organoids
  • Session CodeSP-T07-0208
  • Date & Time / RoomMay 27 (Mon) 14:40~16:10 / Room 321-B
Organizer

Qun Wang (Iowa State University, USA)

Chair

Qun Wang (Iowa State University, USA)

Ying Mei (Clemson University, USA)

Keynote Speaker

14:40~15:05 : Biomaterial toolkits for advanced organoid engineering Seung-Woo Cho (Yonsei University, Korea, Republic of)

Invited Speaker

15:05~15:20 : Engineering a simple and robust organoid on chip to recapitulate full NASH function Hanry Yu (National University of Singapore, Singapore)

Tae-Eun Park (UNIST, Korea, Republic of)

Oral Presenter

15:35~15:45 : Rational design of oral drugs targeting mucosa delivery with gut organoid platforms Qun Wang (Iowa State University, USA)

15:45~15:55 : Multiscale control of nanofiber-composite hydrogel for complex 3D cell culture Chaenyung Cha (Ulsan National Institute of Science and Technology, Korea, Republic of)

15:55~16:05 : In vitro 3D bone organoids based on demineralized bone paper Jungwoo Lee (University of Massachusetts-Amherst, USA)

Description

An organoid is a self-organized 3D tissue typically derived from stem cells (pluripotent, fetal or adult) and mimics an organ's critical functional, structural and biological complexity. Three-dimensional ex vivo organoid cultures using biomaterial-based assembly and self-assembly have been shown to resemble and recapitulate most of the functionality of diverse multicellular tissues and organs, such as the gut, brain, liver, kidney, and lung. They can be dissected and interrogated for fundamental mechanistic studies on human tissue development, regeneration and repair. They can also be used in diagnostics, disease modeling, drug discovery and personalized medicine. Thus, organoids bridge a gap in existing model systems by providing a more stable system amenable to extended cultivation and manipulation while more representative of in vivo physiology. Organoids are typically seeded into biologically derived matrices such as Matrigel, a natural extracellular matrix (ECM) such as collagen, or synthetic hydrogels. However, the defined composition of the biologically derived matrix and the desired control over the biochemical and biophysical spatiotemporal cues are essential for improving organoid culture. This symposium will cover the most recent advancements in biomaterials-mediated organoid and tissue chip technologies in regenerative medicine, cancer therapy, drug testing, environmental control, monitoring, adaptive sensing, and translational applications. This topic was well-received in other scientific meetings and is an exciting emerging research area, such as Society For Biomaterials. This symposium will be helpful for graduate students and postdoctoral fellows to have an overview of the role of organoids in life science and medicine. It also helps engineering and medical professionals increase their awareness of biomimetic strategies in new biomaterials. The symposium will offer presentation and poster opportunities to enhance the workforce's diversity by recruiting students and post-doctorates from underrepresented groups in organoid-related research. In 2024, we will promote translational research to the commercial viability of biomaterials-mediated organoid projects.

 

Keywords : Organoids; Regenerative Medicine; Microenvironments

처음이전1 다음마지막
Top
host
Visitor Counter
  • Total 812,128
  • Today 3,043
  • This week 26,281

WBC 2024 SECRETARIAT

Address
6F, 11-13, Hwarang-ro 8-gil, suseong-gu, Daegu, Republic of Korea (42038)
E-MAIL
(Congress)info.wbc2024@gmail.com
(Sponsorship & Exhibit) exhibition.wbc2024@gmail.com
(Accommodation) wbc2024hotel@gmail.com
(Tour) wbc2024tour@gmail.com

PHONE+82-53-740-0424, 0405

FAX+82-53-742-9007

REGISTRATION NO.138-82-76927

REPRESENTATIVEKi Dong Park

THE KOREAN SOCIETY FOR BIOMATERIALS

Address
502, 22, Teheran-ro 7-gil, Gangnam-gu, Seoul, Republic of Korea (06130)

REGISTRATION NO.209-82-61032

REPRESENTATIVEKun Na

PHONE+82-02-554-9977

FAX+82-02-554-9978

Copyright WBC 2024. All rights reserved