Scientific Program

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  • Session TrackBiomaterials characterization
  • Session TitleDesign, Fabrication and Evaluation of Biomedical Textiles
  • Session CodeSP-T05-0318
  • Date & Time / RoomMay 28 (Tue) 16:30~18:00 / Room 321-A
Organizer

Martin W. King (North Carolina State University, USA)

Chair

Martin W. King (North Carolina State University, USA)

Fujun Wang (Donghua University, China)

Keynote Speaker

16:30~16:55 : Advanced Textile Structural Devices for Load-Bearing Soft Tissue High Quality Repair Lu Wang (Donghua University, China)

Invited Speaker

16:55~17:10 : Fabrication of barbed sutures using a laser system for reconstructive surgery Martin W. King (North Carolina State University, USA)

Ze Zhang (CHU de Quebec, Universite Laval, Canada)

17:25~17:40 : Advances in the in vivo evaluation of a tissue-engineered vascular graft made by weaving threads of cell-assembled extracellular matrix Nicolas L'Heureux (Université de Bordeaux, France)

Oral Presenter

17:40~17:50 : Preparation and characterization of silk fibroin-based biomaterial film from Antheraea frithi Moore cocoon for potential biomedical applications Sanasam Yaiphabi (Manipur University, India)

17:50~18:00 : Braided silk fibroin artificial ligament combining with gradient hydrogel for ligament-bone integration Guoping GUAN (Donghua University, China)

Description

This symposium will focus on the design concepts, the fabrication methods and the evaluation protocols of textile-based biomedical devices used for disease and injury prevention, monitoring and treatment.  The content will include fiber-based material design, biotextile processing and forming techniques as well as surface modification, biomechanics, biocompatibility and advances in biofunctional strategies to improve textile based biomedical devices. The symposium will highlight the distinct advantages of using textile processing technologies, such as weaving, knitting, braiding, nonwovens production and composite fabrication to provide strong, flexible devices with precisely controlled total porosity and pore size distribution. 



So if you are a biomaterials scientist or biomedical engineer working in an institution or in a company, you will be aware of the need for several stage / gate decisions as the original biomaterials design concept moves through the "New Product Development" process to eventually reach launch and sales.  An important component of this process is to understand the value of the innovation from both the clinician's and the patient's point of view.  By including contributions for researchers at different points along the "New Product Development" process, it is anticipated that this symposium will improve our understanding of not only the technical and scientific advances of textile-based biomaterals, but also how to move a unique innovative concept all the way through the business product development procees so that clinicians and patients can benefit from the original idea.  

Keywords : textiles, fabrication, characterization

  • Session TrackBiomaterials characterization
  • Session TitleBioinspired antimicrobial and hemocompatible materials
  • Session CodeSP-T05-0329
  • Date & Time / RoomMay 29 (Wed) 9:30~11:00 / Room 321-A
Organizer

Elizabeth Brisbois (University of Georgia, USA)

Chair

Elizabeth Brisbois (University of Georgia, USA)

Hitesh Handa (University of Georgia, USA)

Keynote Speaker

9:30~9:55 : Combinatorial approaches for improved biocompatibility Christopher Siedlecki (Penn State University, USA)

Invited Speaker

9:55~10:10 : Bioinspired endothelium-mimicking surface for blood-contacting medical devices Hitesh Handa (University of Georgia, USA)

Oral Presenter

10:10~10:20 : Photoactive nitric oxide release for enhanced antimicrobial biointerfaces Elizabeth Brisbois (University of Georgia, USA)

10:20~10:30 : An in vivo imaging model to study the cellular foreign body response and infection resistance of novel implant coatings Elles Boonstra (UMCG, Netherlands)

10:30~10:40 : Polypyrrole-based conductive fibers and textiles for biomedical applications Jifu Mao (Donghua University, China)

10:40~10:50 : Platelet membrane coated Cu-based layered double hydroxide nanoparticles as an endothelial nitric oxide synthase mimic for atherosclerosis treatment jiawei cui (Southwest Jiaotong university, China)

10:50~11:00 : A mechanically resilient and tissue-conformable hydrogel with hemostatic and antibacterial capabilities for wound care tae young kim (Yonsei university, Korea, Republic of)

Description

Objective and Proposed Programming:  Clinical applications of medical devices suffer from major challenges of thrombosis, biofouling, and infection.  Treatment of microbial infections is complicated by rising antibiotic resistance and the inherent difficulty of treating biofilm-associated infections. In both scenarios, many current FDA approved antimicrobial drugs are ineffective, leading to a significant health and economic burden. Advances in antimicrobial biomaterial therapies have the potential to improve outcomes for bacterial, fungal, viral, and biofilm-associated infections. Innovations in biomaterials are critically needed in the face of the COVID-19 pandemic, both for treatments of the SARS-CoV-2 virus, and also for effective treatment of the severe bacterial and fungal co-infections and biofilms that have been reported.



Similarly, nonthrombogenic surfaces that are clinically available are designed to inhibit fibrin formation, but do not prevent platelet activation and are minimally effective. Thrombus and biofilm formation are highly related, where fouling of these devices is the most common clinical complication, either through protein adsorption leading to thrombus formation or bacterial adhesion resulting in infection

This session will cover latest developments in bioinspired biomaterials approaches to treat bacterial, fungal, and viral infections, including the prevention of thrombosis and eradication of biofilms and thrombosis. Topics discussed may include antimicrobial and hemocompatible surface modifications, device coatings, drug delivery, protein/blood/bacteria/virus-surface interactions, in vitro and in vivo biocompatibility characterization studies.



Intended Audience:  Academic, clinical, government, and industrial researchers.



Relevance and Expected Outcomes: This session fits well within the mission of  WBC to discuss the design and characterization of biomaterials for some of the most critical medical device applications, ultimately aimed at improving patient care.  This session will bring together key stakeholders of this field and encourage international collaboration on this timely field.

Keywords : antimicrobial, hemocompatible, bioinspired

  • Session TrackBiomaterials characterization
  • Session TitleCharacterization of biodegradable metals
  • Session CodeSP-T05-0333
  • Date & Time / RoomMay 27 (Mon) 13:00~14:30 / Room 321-A
Organizer

Hyung-Seop Han (Center for Biomaterials/ Korea Insitute of Science and Technology, Korea, Republic of)

Chair

Hyung-Seop Han (Center for Biomaterials/ Korea Insitute of Science and Technology, Korea, Republic of)

SangIhn Han (Center for Biomaterials, Biomedical Research Division, Korea Institute of Science and Technology, Korea, Republic of)

Keynote Speaker

13:00~13:25 : Evidences and challenges in the characterization of bioabsorbable metals based on Fe, Mg, Zn for temporary medical devices Diego Mantovani (Department of Mining, Metallurgical and Materials Engineering/Laval University, Canada)

Invited Speaker

13:25~13:40 : Study on the biodegradation behavior of pure molybdenum Yufeng Zheng (School of Materials Science and Engineering/Peking University, China)

13:40~13:55 : 3D-Printed Intelligent Biodegradable Implant Seung-Kyun Kang (Materials Science and Engineering/Seoul National University, Korea, Republic of)

13:55~14:10 : R & D and application of biomedical High purity Mg materials with high strength Zhentao Yu (Jinan University, China)

Oral Presenter

14:10~14:20 : Surface finishing electropolishing processes for additively manufactured Fe-based biodegradable metals contacting blood Marta Multigner (Rey Juan Carlos University, Spain)

14:20~14:30 : Development and clinical translation of biodegradable high-purity magnesium internal fixation screw Dewei Zhao (Affliated Zhongshan Hospital of Dalian University, China)

Description

 The interest in biocompatible and biodegradable metals, such as magnesium, is mainly related to their potential use as structural material for orthopedic and cardiovascular applications where a temporary medical device is required. This symposium aims to discuss open questions on the session topics, new approaches, background knowledge, and personal views among the participants.



 Keynote speakers will deliver a presentation regarding the current status and outlook on the field of biodegradable metals which will be intended for the general audience working in biomaterials field.



 It is expected to bring huge interest and audience to the sessions as biodegradable metallic materials has shown the feasibility of these novel materials for use in the fields of cardiology and orthopedics. It is highly relevant to the main topic of SBC 2024 as the symposium aims to explore and introduce innovative strategies to overcome the current limitations of magnesium.

Keywords : Biomaterial Characterization, Biodegradable Metal, Bioactive Materials

  • Session TrackBiomaterials characterization
  • Session TitleCharacterization of cell-scaffold interface in nanoscale for therapeutic applications
  • Session CodeSP-T05-0334
  • Date & Time / RoomMay 27 (Mon) 14:40~16:10 / Room 321-A
Organizer

Jangho Kim (Chonnam National University, Korea, Republic of)

Chair

Jangho Kim (Chonnam National University, Korea, Republic of)

Sunwoo Hoon (Sunchon National University, Korea, Republic of)

Keynote Speaker

Jin-Woo Kim (University of Arkansas, USA)

Invited Speaker

15:05~15:20 : Brain-on-a-Chip Technology for Modeling Human Brain Diseases Hong Nam Kim (KIST, Korea, Republic of)

15:20~15:35 : Enhancement of In Vitro Osteogenesis Using Alkaline Hydrolysis Modified 3D-Printed Poly(ε-Caprolactone)/Hydroxyapatite Scaffolds Kyoung Je Jang (Gyeongsang National University, Korea, Republic of)

Oral Presenter

15:35~15:45 : Material characterization and parameter identification of periodontal ligament considering tension-compression asymmetric moduli and nonlinear behavior Shaoyang Bi (Tianjin University, China)

15:45~15:55 : Hernia mesh with biomechanical and mesh–tissue interface dual compliance for scarless abdominal wall reconstruction Chaojing Li (Donghua University, China)

15:55~16:05 : Preparation and biological evaluation of porous tantalum scaffolds coated with copper-doped hydroxyapatite Xie Hui (Affiliated Zhongshan Hospital of Dalian University, China)

Description

The objective of this symposium is to provide most recent information about the characterization of cell-scaffold interface in nanoscale for therapeutic applications. In this session, the innovative micro- and nanoscale engineering tools developed in combination with traditional molecular, cell biology, and live cell imaging approaches will be proposed to investigate various physiological and disease processes in the living systems. We believe that our session may give useful values for WBC 2024 audience who may enjoy designing and manipulate nanoscale biomaterial platforms, especially for therapeutic applications.

Keywords : Biomaterials Characterization, Cell-scaffold Interface in Nanoscale, Therapeutic Applications

  • Session TrackBiomaterials characterization
  • Session TitleBio-fabrication/bioprinting and characterization for biomedical application
  • Session CodeSP-T05-0335
  • Date & Time / RoomMay 27 (Mon) 16:30~18:00 / Room 321-A
Organizer

Suk Ho Bhang (School of Chemical Engineering / Sungkyunkwan University, Korea, Republic of)

Chair

Suk Ho Bhang (School of Chemical Engineering / Sungkyunkwan University, Korea, Republic of)

Hyun-Ji Park (Department of Applied Chemistry and Biological Engineering / Ajou University, Korea, Republic of)

Keynote Speaker

16:30~16:55 : Engineering scaffold-free tissue constructs via modular assembly, cell-only bioprinting and 4D strategies Eben Alsberg (Departments of Biomedical Engineering, Mechanical & Industrial Engineering, Pharmacology and Regenerative Medicine, and Orthopaedic Surgery / University of Illinois Chicago, USA)

Invited Speaker

16:55~17:10 : Repurposing Antiviral Peptides for Tumor-Derived Exosome Inhibition and Cancer Immunotherapy Enhancement: A Membrane Biophysics Perspective Jackman Joshua A. (School of Chemical Engineering, Sungkyunkwan University, USA)

17:10~17:25 : Multilevel neurium-mimetic individualized graft via a sugar painting-inspired additive manufacturing for peripheral nerve injuries Wei Sun (State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, China)

Oral Presenter

17:25~17:35 : Printing and full characterization of metamaterials using shape memory alloys for a new generation of smart personalized implants MONICA ECHEVERRY RENDON (IMDEA Materials, Spain)

17:35~17:45 : 3D Printed Ti6Al4V Porous Implant Surface Functionalization by Ultraviolet LED Chuan Yin (Shanghai Ninth People's Hospital Affiliated Shanghai JiaoTong University School of Medicine, China)

17:45~17:55 : Towards a Cystic Fibrosis-Biofilm model: Acetylation of alginate and its influence on physicochemical properties Stephan Schandl (TU Wien, Austria)

Description

The objective of this symposium is to introduce novel and recent knowledge and technique related to the biomaterial characterization. In this session, the bio-fabrication, bioprinting, and biotechnology in interfacial science and biosensors will be proposed. We believe that this session may provide beneficial and helpful information. Researchers who are interested in bio-fabrication, bioprinting, and biotechnology in interfacial science and biosensors are welcome to join the session and exchange ideas for research and future collaboration. The intended audience for this session is likely to be the scientists and researchers in the field of biomaterial science, 3D- and 4D bioprinting, biosensors, cell and tissue engineering for biomedical application.

Keywords : Biomaterial characterization, Bio-fabrication/bioprinting, Biomedical application

  • Session TrackBiomaterials characterization
  • Session TitleMaterials and characterizations for cardiovascular applications
  • Session CodeSP-T05-0336
  • Date & Time / RoomMay 28 (Tue) 9:30~11:00 / Room 321-A
Organizer

Hyun-Ji Park (Ajou University, Korea, Republic of)

Chair

Hyun-Ji Park (Ajou University, Korea, Republic of)

Suk Ho Bhang (Sungkyunkwan University, Korea, Republic of)

Keynote Speaker

Michael Davis (Emory University and Georgia Institute of Technology, USA)

Invited Speaker

9:55~10:10 : Underwater acoustic levitation technology that forms ultra-fast 3D cell aggregates and improves the therapeutic efficacy of the aggregates Suk Ho Bhang (Sungkyunkwan University, Korea, Republic of)

Soah Lee (Sungkyunkwan University, Korea, Republic of)

Oral Presenter

10:25~10:35 : Recombinant spider silk for cardiovascular applications: biodegradable, drug eluting, and endothelial cell-specific materials Daniel Heath (University of Melbourne, Australia)

10:35~10:45 : Reinforced composite hydrogels with Wharton`s jelly stromal cells for vascular patches Simon Prazak (Institute of Physiology CAS, Czech Republic)

10:45~10:55 : Bioactive coatings for enhancing the corrosion resistance and biocompatibility of magnesium alloys for cardiovascular stents Changjiang Pan (Changzhou University, China)

Description

The purpose of this symposium is to bring together experts from biomechanics, bioengineering, and cardiology, to exchange ideas on research that aims to improve the diagnosis, treatment, and prevention of cardiovascular diseases. The goal is to explore the use of various materials, such as polymers, ceramics, and metals, that can be used to improve the quality of life for patients with cardiovascular conditions. The symposium will also include presentations and discussions on the latest techniques and methods for caharacterizing these materials, including mechanical testing, imaging, and biomaterials evaluation, and also to discuss how these new materials and characterization techniques are being translated into clinical practice. The intended audience for this symposium is likely to be the scientists and researchers in the field of cardiovascular materials and characterizations, including materials scientists, bioengineers, and biomedical engineers.

Keywords : Cardiovascular, Cardiac

  • Session TrackBiomaterials characterization
  • Session TitleApplications for Biomedical Fibrous Materials
  • Session CodeSP-T05-0391
  • Date & Time / RoomMay 29 (Wed) 13:40~15:10 / Room 321-A
Organizer

Martin W. King (North Carolina State University, USA)

Chair

Martin W. King (North Carolina State University, USA)

Xiumei Mo (Donghua University, China)

Keynote Speaker

13:40~14:05 : Tissue Engineered Cardiovascular Devices: Potential and Limits of Fibers Frédéric Heim (Université de Haute Alsace, France)

Invited Speaker

14:05~14:20 : Innovations in the Biomedical Fibrous Materials Seeram Ramakrishna (National University of Singapore, Singapore)

14:20~14:35 : Fiber-reinforced hydrogel: bridging strength and bioactivity for vascular tissue engineering Fan Zhang (University of Washington, USA)

Oral Presenter

14:35~14:45 : RENACER®: A non-toxic, fully resorbable and environmentally friendly fibrous biomaterial platform Bastian Christ (Fraunhofer Insitute for Silicate Research ISC, Germany)

14:45~14:55 : Plant-derived polyphenol and LL-37 peptide-modified nanofibrous scaffolds for promotion of antibacterial activity, anti-Inflammation, and type‑H vascularized bone regeneration Jin Shu'e (Sichuan University, China)

14:55~15:05 : One-pot functionalization of biomedical surfaces by silk fibroin self-assembly R. Helen Zha (Rensselaer Polytechnic Institute, USA)

Description

The success of designing and fabricating functional tissue engineering scaffolds has been limited by slow tissue regeneration and inflammatory complications. The use of resorbable fiber-based textile scaffolds can precisely control the porosity of the construct through the thickness, and provide sufficient mechanical support to promote dimensional stability as well as cellular infiltration prior to resorption.



Studies have also identified the critical role of macrophages which have been modulated to different phenotypes in the regeneration and remodeling of tissue engineering constructs. There is evidence to demonstrate that the distribution of porosity, such as a porosity gradient, can downregulated the M1 macrophage gene expression and upregulated M2 gene expression during in vitro cell culture, and hence promote healthy tissue regeneration.



In this symposium, we will hear from research scientists and engineers, clinicians, and manufacturers about their use of resorbable fiber-based textile-reinforced scaffolds to promote cell proliferation, migration and complete healing for a wide variety of clinical applications, such as cardiovascular repair, surgical sutures, hernia and drug delivery meshes, knee ligament replacement, corneal ophthalmology regeneration, orthopedic tendon repair and wound dressings.

Keywords : tissue engineering, scaffold, resorbable fiber

  • Session TrackBiomaterials characterization
  • Session TitleAntifouling biomaterials and surface characterization
  • Session CodeSP-T05-0148
  • Date & Time / RoomMay 28 (Tue) 13:40~15:10 / Room 321-A
Organizer

Yoon Ki Joung (Korea Institute of Science and Technology, Korea, Republic of)

Chair

Yoon Ki Joung (Korea Institute of Science and Technology, Korea, Republic of)

Sung-Hwan Choi (Yonsei University College of Dentistry, Korea, Republic of)

Keynote Speaker

13:40~14:05 : Zwitterionic Materials for Biomedical Applications Shaoyi Jiang (Cornell University, USA)

Invited Speaker

14:05~14:20 : Harnessing nature’s blueprints to design antifouling interactive biointerfaces César Rodriguez-Emmenegger (DWI – Leibniz-Institut für Interaktive Materialien, Germany)

14:20~14:35 : Antifouling bioactive materials using zwitterions Sung-Hwan Choi (Yonsei University College of Dentistry, Korea, Republic of)

Oral Presenter

14:35~14:45 : Surface-protein interactions on additively manufactured CoCr alloy for biomedical application Thomas Luxbacher (Anton Paar GmbH, Austria)

14:45~14:55 : The attachment and conformation of fibrinogen and albumin controlled by PAMAM-NH2/-COOH and the thermodynamic-interaction between PAMAM and proteins LI LI (Xihua University, China)

14:55~15:05 : Combined Use of Polycarboxybetaine Coatings with a Selective FXIIa Inhibitor to Create Potent Anticoagulation without Bleeding during ECLS Suji Shin (Carnegie Mellon University, USA)

Description

The objective of the symposium is to introduce antifouling biomaterials that can be used as a lot of invasive, interventional, and implantable medical devices, expecting anti-thrombogenicity, anti-bacterial effect, biocompatibility, and so on. All keynote and invited speakers will cover the field of chemically surface-modified biomaterials with keywords such as antifouling, anti-thrombosis, anti-bacterial, anti-infectious, surface modification, and zwitterionic polymers. Relevant audiences can be all scientists interested in biomaterials, chemistry, materials science, surface science, translational research, and so on.

Keywords : Surface modification, Antifouling, Bio-interface

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WBC 2024 SECRETARIAT

Address
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THE KOREAN SOCIETY FOR BIOMATERIALS

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